18ĮOne patient randomized to conventional oxygen therapy received high-flow oxygen therapy according to the decision of the attending physician. Child-Pugh class C is a total score of more than 9 points. Global Initiative for Chronic Obstructive Lung Disease (GOLD) airflow limitations are determined by spirometry and divided into 4 grades: 1, mild (forced expiratory volume in first second of expiration ≥80% predicted) 2, moderate (FEV 1 50%-79% predicted) 3, severe (FEV 1 30%-49% predicted) and 4, very severe (FEV 1 3.0 mg/dL), serum albumin level (1 point for ≥3.5 g/dL, 2 points for 2.8-3.5 g/dL, and 3 points for 6 seconds), and encephalopathy (1 point for none, 2 points for grade 1 or 2, and 3 points for grade 3 or 4). 16ĬCOPD indicates chronic obstructive pulmonary disease. ![]() Patients for whom therapeutic limitations were anticipated or moribund patients were included in this category.īNew York Heart Association (NYHA) class I indicates no symptoms with normal physical activity (asymptomatic) class II, mild symptoms with normal physical activity class III, moderate symptoms with activities of daily living and class IV, symptoms at rest. ![]() ADefined as any serious medical condition or clinical laboratory test result abnormality that, in an investigator’s judgement, could prevent safe patient participation and completion of the study.
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